Trachelogenin, an HCV entry inhibitor, has antiproliferative effects, and its mechanism is related to affecting the phosphorylation of key proteins in the β-Catenin signaling pathway, such as β-Catenin, c-Myc, and GSK3, in a concentration-dependent manner.

Hypertrehalosaemic Neuropeptide, Heliothis zea

Uprosertib (GSK2141795) 是一种选择性、ATP 竞争性、口服生物可利用的 Akt 抑制剂，对 Akt 1、2 和 3 的 IC50 值分别为 180 nM、328 nM 和 38 nM。